This is the question taken on by Fr. John Behr, dean and Patristics professor at St. Vladimir’s Seminary.  The discussion of this question lasts for this next week.  If you’re interested in this question, go here:

http://bigquestionsonline.com/content/god-wholly-separate-material-universe

This should apply to anyone interested in “how” God works in the world, “if” God works in the world, “if” there is a God, “whether” science can find God, etc.